La revisión se enmarca en las terapias cognitivo-conductuales (conjunto de terapias que combinan elementos del conductismo y la terapia cognitiva). La misma busca como objetivo principal, revisar la bibliografía existente respecto a tratamientos para la ansiedad, comparando el desempeño del Protocolo Unificado de Barlow (tratamiento transdiagnóstico, que trata aspectos comunes subyacentes a las psicopatologías) con el de los tratamientos de trastorno único (tratamientos específicos para cada patología). Se buscó en los buscadores Cochrane y Pubmed. Se utilizaron las palabras claves “cognitive behavioural therapy”, “Barlow”, “unified protocol”, “UP”, “transdiagnostic”, “transdiagnostic treatment”, “unified protocol for transdiagnostic treatment of anxiety”, “single disorder treatment”, “diagnosis specific” y “anxiety”. Se incluyeron artículos en inglés (y español) desde el año 2020 (agosto) hasta el presente e investigaciones con pacientes de todas las edades y sexos. Se excluyeron los artículos que no hablaran de tratamientos psicológicos (por ejemplo, tratamientos médicos), que no hablaran del tratamiento de la ansiedad, que no compararan el protocolo unificado de Barlow con tratamientos de trastorno único, que no fueran en español o inglés y estudios con diseño metodológico insuficiente o inadecuado o sin información detallada sobre los métodos y resultados. Se presentarán y discutirán los resultados. Palabras clave Protocolo Unificado - Trastornos de la ansiedad - Trastorno único - TCC ABSTRACT COMPARISON BETWEEN THE PERFORMANCE OF BARLOW´S UNIFIED PROTOCOL AND SINGLE DISORDER TREATMENTS IN THE TREATMENT OF ANXIETY DISORDERS The review is framed in cognitive-behavioral therapies (a set of therapies that combine elements of behavioral and cognitive therapy). Its main objective is to review the existing literature regarding treatments for anxiety, comparing the performance of the Unified Barlow Protocol (transdiagnostic treatment, which treats common aspects underlying psychopathologies) with the performance of single disorder treatments (specific treatments for each pathology). The Cochrane and Pubmed search engines were searched, and key words “cognitive behavioral therapy”, “Barlow”, “unified protocol”, “UP”, “transdiagnostic”, “transdiagnostic treatment”, “unified protocol for transdiagnostic treatment of anxiety”, “single disorder treatment”, “diagnosis specific” and “anxiety” were used. Articles in English (and Spanish) from 2020 (August) to the present and research with patients of all ages and sexes, were included. Articles that did not discuss psychological treatments (e.g., medical treatments), did not discuss anxiety treatment, did not compare Barlow’s unified protocol with single-disorder treatments, which were not in Spanish or English and studies with insufficient or inadequate methodological design or without detailed information on methods and results, were excluded. The results will be presented and discussed. Keywords Unified Protocol - Anxiety disorders - Single disorder treatments