This chapter presents a review of the socio-historic and cultural knowledge that conditions the ways of understanding, interpreting, and relating in and with the natural world from an intercultural perspective on the part of the local indigenous inhabitants of the natural protected areas (NPA) of Latin America. The Good Living theory will be the philosophical approach to develop the present analysis, from the ancestral indigenous American perspective, which is considered an integrating theoretical framework with a cosmic approach and not anthropocentric.