Mariátegui is undoubtedly one of the most important Marxist figures in Latin America, its enormous spectral scope of project and counter-hegemonic thinking does not disappear in the time of yesterday and today. For many, it is with José Carlos Mariátegui that it begins and ends in space that is the convergence of the pastpresent-future, three times that are articulated under the same reality. Finally, they all turn out to be a chain of the same historical process marked by powerful catalyst forces and eternal resistances. Mariátegui (2007) understood that the Gospel constituted being for Andean societies, an inexorable destiny for which they would be ousted through worship and the liturgy, the latter two conforming to the deepest customs of the indigenous. On this elementary idea, we seek to analyze the collision of two diametrically opposed empires from mythical-religious terrain. Feeding this scene, an inventory of narratives, omens and future misfortunes of how that Inca Empire would end in 1533 and the so-called Resistances of Vilcabamba in 1572. In this way, this analysis merges into mythical structural thinking, the same one that allows to reconstruct the socio-Andean retrospective representations with the fact that we can stamp these reflections to the present. After 500 years of that meeting, a point has been reached where, far apart from granting exchanges and processes of religious mestizajes, there are also solid encounters that cross the Andes, and which today resist, no matter what.