El objetivo del presente trabajo fue realizar tanto una conceptualización sobre el estigma como una revisión sobre investigaciones realizadas acerca del estigma en usuarios de salud mental con trastorno mental grave en Latinoamérica, principalmente en Argentina. Para hacerlo, se consideró la literatura existente previamente y se exploró en bases de datos como Google Académico, Lilacs y PubMed, utilizando los términos “estigma mental”; “Argentina”; “Latinoamérica”; “autoestigma”; “salud”. Se encontraron diferentes artículos de los que se seleccionaron cinco, ya que se centraron en investigaciones realizadas en esta región, durante la última década. A raíz de estos estudios, se concluye que, a diferencia de otros países, son pocas las investigaciones que se hicieron con respecto a este problema en Argentina y, además, los resultados arribados son contradictorios. Por lo tanto, es necesario continuar investigando sobre el tema. Palabras clave Estigma - Trastorno mental grave - Usuarios - Salud Mental ABSTRACT STIGMA IN MENTAL HEALTH SERVICE USERS WITH SEVERE MENTAL DISORDER The objective of this study was to carry out both a conceptualization on stigma and a review of research conducted on stigma in mental health service users with severe mental disorders in Latin America, mainly in Argentina. To do so, the previously existing literature was considered and explored in databases such as Google Scholar, Lilacs and PubMed, using the terms “mental stigma”; “Argentina”; “Latin America”; “Self-stigma”; “Health”. Different articles were found, which five were selected since they focused on research carried out in this region during the last decade. As a result of these studies, it is concluded that, unlike other countries, there are few investigations that were made with regards to this problem in Argentina, additionally, the results arrived at are contradictory. Therefore, it is necessary to continue researching the subject. Key words Stigma - Severe mental disorders - Users - Mental Health