El presente proyecto parte de la reformulación que Lacan realiza en los años setenta del concepto de síntoma, señalando que éste no solo implica una operación de sustitución significante -la metáforasino que comporta una satisfacción paradojal, resistente al sentido y residual en el análisis. Durante el último período de su enseñanza la problemática de lo real del síntoma presentará abordajes sucesivos y cambiantes así como sus articulaciones con los conceptos de signo, cifra, letra y sentido, elaborados en la misma época. Palabras clave Síntoma, Sentido, Real ABSTRACT THE SYMPTOM,THE SENSE AND THE REAL IN THE LAST PERIOD OF JACQUES LACAN´S TEACHING The current project begins with the reformulation that Lacan makes of the concept of symptom in the seventies, when he points out that it does not consist only in a significant replacement operation - the metaphor - but it also involves a paradoxical satisfaction, which is sense resistant and residual in the analysis process. During the last period of his teaching the problematic about the real of the symptom will present successive and changing approaches as well as its relationships with some other concepts like sign, cypher, letter and sense, elaborated during the same period. Key words Symptom, Sense, Real